{"id":5,"date":"2009-10-06T10:17:21","date_gmt":"2009-10-06T14:17:21","guid":{"rendered":"http:\/\/www.sgcappsphd.com\/?p=5"},"modified":"2010-05-04T09:45:26","modified_gmt":"2010-05-04T13:45:26","slug":"understanding-biomechanical-engineering-language","status":"publish","type":"post","link":"https:\/\/sgcappsphd.com\/?p=5","title":{"rendered":"Understanding Biomechanical Engineering Language"},"content":{"rendered":"<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">Structures and Materials<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">Let\u2019s begin with the difference between \u201cstructures\u201d and \u201cmaterials\u201d. An easy way to remember the distinction is to visualize a building in its early stages of construction. It looks like a huge, complex, erector-set of connected steel beams. The skeletal building is a structure, its properties and behaviors are functions of its geometry, connections, and material. The properties of the material, steel, are dependent on the alloy content and the processing that created it.<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">Another illustration: the spine. The spine is a structure made of vertebral bodies and intervertebral discs. The vertebrae are also structures in their own right; primarily made of a cortical bone \u201cshell\u201d and a cancellous bone \u201cfilling\u201d. To the naked-eye, cortical bone is a material and cancellous bone is a structure. After all, the beam-and-truss \u201cconstruction\u201d of cancellous bone is easy to see. The small, individual \u201cbeams\u201d and \u201ctrusses\u201d are the true bone in cancellous bone. On the microscopic level, neither cortical nor cancellous bone are materials, they\u2019re both structures and the individual components, such as calcium phosphate crystals and collagen, are the materials.<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">Just as the structural properties of the building under-construction are dependent on the alloy and its processing, the structural properties of the spine are dependent on the bone and its health. Osteoporosis affects the strength of bone through the removal of material and the creation of voids. Age affects the strength of intervertebral discs through changes in collagen.<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">The Basics<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">The properties of biological tissues are determined by the analysis of structural testing output, often in the form of load versus displacement diagrams [Figure 1]. Each load versus displacement diagram for biological tissues is unique. Not only do the diagrams differ from type of tissue, such as bone and cartilage, they also differ by location, for example the distal radius and the proximal femur. Load versus displacement diagrams also differ with age and health status, the peak load for osteoporotic bone will be less than for healthy, non-osteoporotic bone. This peak load, known as the ultimate load is the point where force and displacement create irretrievable damage to the biological tissue; it is the load where failure occurs (a.k.a. \u201cfailure load\u201d).<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">\u201cLoad\u201d, also known as \u201cforce\u201d, is the external pull or push applied to an object; the units of force are Newtons (N) or pounds (lbs) [Figure 2]. \u201cDisplacement\u201d is the difference in the position of a particular point from the initial, unloaded condition to the final, loaded condition. \u201cDeformation\u201d is the relative displacement of any two points in a body. Displacement and deformation have units of length; meters (m), feet (ft), or inches (in) [Figure 3].<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">Stiffness is represented by the slope of the straight line on force-displacement diagrams and has units of force per deformation, Newtons per meter (N\/m) or pounds per inch (lb\/in). Stiffer materials, like bone, are more resistant to deformation at a given load than less stiff materials like cartilage [Figure 4].<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">Strength, Elasticity, and Viscoelasticity<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">Although load and strength or stiffness and elasticity are often used interchangeably, they are not the same. Load and stiffness are properties described by force-displacement diagrams while strength and elasticity are properties described by stress versus strain diagrams [Figure 5]. These diagrams are very similar in appearance to load-displacement diagrams, but they represent strength not failure load and elasticity not stiffness.<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">\u201cStress\u201d refers to the forces within an object. The intensity of the internal force over the cut section is stress and is defined as the force per unit area over which the force is acting [\u03c3 = F\/A]. Figure 6 illustrates \u201cnormal stress\u201d, meaning stress that is perpendicular to the plane of the cut; stress is measured as force per unit area and has units of MPa (N\/m2) or psi (lb\/in2). \u201cStrength\u201d is analogous to \u201cfailure load\u201d, it is a measure of the compressive force at the exact instant of failure.<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">\u201cStrain\u201d is unit deformation, a measure of the degree or intensity of deformation. Strain is the ratio of change in length (increase or decrease) to original length [\u0454 = \u2206l\/l], and therefore has no units of measure [Figure 7]. When a body is in tension, its length increases and strain is positive. When a body is in compression, its length decreases and strain is negative.<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">\u201cElasticity\u201d is defined by Hooke\u2019s Law, E = \u03c3\/ \u0454, and is represented by the slope of the straight line on stress-strain diagrams. Elasticity has units of MPa or psi. Within the elastic range, the straight line portion of the stress-strain diagram, deformation is reversible by simply removing the load; for example, a rubber band after being stretched will return to it\u2019s original shape. In the non-linear portion of the stress-strain curve, deformation is plastic and non-reversible; potters clay is a good example of \u00a0plastic behavior.<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">But, few biological tissues obey Hooke\u2019s Law, they actually behave as viscoelastic (a.k.a. viscoplastic) solids. There are two basic properties that describe their behavior: strength and stiffness. Cancellous bone is a viscoplastic biological structure. When cancellous bone is loaded quickly, it behaves as a fairly stiff material, it is resistant to deformation AND it tends to support higher loads. When cancellous bone is loaded slowly, it behaves as a less stiff material. \u201cVisco\u201d because cancellous bone deforms as a function of time. \u201cPlastic\u201d because once it deforms, cancellous bone doesn\u2019t recover much, if any, of its original shape.<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">Final Thoughts<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">This is a very brief \u201ctaste\u201d of biomechanical engineering as it relates to the properties and behavior of orthopaedic tissues. A more detailed discussion would include advanced testing techniques such as impact and fatigue testing, properties like ductility and toughness, and influences from age, gender, and disease.<\/div>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow-x: hidden; overflow-y: hidden;\">Please feel free to contact me with any thoughts or inquiries.<\/div>\n<p>Biomechanical engineering describes the properties and the behavior of biological tissues using mechanical engineering principles and terms. Words such as \u201cload\u201d, \u201cforce\u201d, \u201cstress\u201d, \u201cstrength\u201d and \u201cstiffness\u201d populate marketing materials, white papers, journal articles, and popular media. Bone, cartilage, ligaments, and implants are described using this vocabulary. Unfortunately, these terms are frequently misused and\/or misunderstood by both authors and readers. This mini-tutorial on biomechanical engineering will clarify some of the more common language and its engineering definitions.<\/p>\n<h2>Structures and Materials<\/h2>\n<p>Let\u2019s begin with the difference between \u201cstructures\u201d and \u201cmaterials\u201d. An easy way to remember the distinction is to visualize a building in its early stages of construction. It looks like a huge, complex, erector-set of connected steel beams. The skeletal building is a structure, its properties and behaviors are functions of its geometry, connections, and material. The properties of the material, steel, are dependent on the alloy content and the processing that created it.<\/p>\n<p>Another illustration: the spine. The spine is a structure made of vertebral bodies and intervertebral discs. The vertebrae are also structures in their own right; primarily made of a cortical bone \u201cshell\u201d and a cancellous bone \u201cfilling\u201d. To the naked-eye, cortical bone is a material and cancellous bone is a structure. After all, the beam-and-truss \u201cconstruction\u201d of cancellous bone is easy to see. The small, individual \u201cbeams\u201d and \u201ctrusses\u201d are the true bone in cancellous bone. On the microscopic level, neither cortical nor cancellous bone are materials, they\u2019re both structures and the individual components, such as calcium phosphate crystals and collagen, are the materials.<\/p>\n<p>Just as the structural properties of the building under-construction are dependent on the alloy and its processing, the structural properties of the spine are dependent on the bone and its health. Osteoporosis affects the strength of bone through the removal of material and the creation of voids. Age affects the strength of intervertebral discs through changes in collagen.<!--more--><\/p>\n<h2><strong>The Basics<\/strong><\/h2>\n<p>The properties of biological tissues are determined by the analysis of structural testing output, often in the form of load versus displacement diagrams [Figure 1]. Each load versus displacement diagram for biological tissues is unique. Not only do the diagrams differ from type of tissue, such as bone and cartilage, they also differ by location, for example the distal radius and the proximal femur. Load versus displacement diagrams also differ with age and health status, the peak load for osteoporotic bone will be less than for healthy, non-osteoporotic bone. This peak load, known as the ultimate load is the point where force and displacement create irretrievable damage to the biological tissue; it is the load where failure occurs (a.k.a. \u201cfailure load\u201d).<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" title=\"Fig1 biomechl language 091005\" src=\"http:\/\/www.sgcappsphd.com\/wp-content\/uploads\/2009\/10\/Fig1-biomechl-language-091005.png\" alt=\"Fig1 biomechl language 091005\" width=\"220\" height=\"153\" \/><\/p>\n<p>\u201cLoad\u201d, also known as \u201cforce\u201d, is the external pull or push applied to an object; the units of force are Newtons (N) or pounds (lbs) [Figure 2]. \u201cDisplacement\u201d is the difference in the position of a particular point from the initial, unloaded condition to the final, loaded condition. \u201cDeformation\u201d is the relative displacement of any two points in a body. Displacement and deformation have units of length; meters (m), feet (ft), or inches (in) [Figure 3].<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-11\" title=\"Fig2 biomechl language 091005\" src=\"http:\/\/www.sgcappsphd.com\/wp-content\/uploads\/2009\/10\/Fig2-biomechl-language-091005.png\" alt=\"Fig2 biomechl language 091005\" width=\"220\" height=\"124\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-12\" title=\"Fig3 biomechl language 091005\" src=\"http:\/\/www.sgcappsphd.com\/wp-content\/uploads\/2009\/10\/Fig3-biomechl-language-091005.png\" alt=\"Fig3 biomechl language 091005\" width=\"328\" height=\"114\" srcset=\"https:\/\/sgcappsphd.com\/wp-content\/uploads\/2009\/10\/Fig3-biomechl-language-091005.png 328w, https:\/\/sgcappsphd.com\/wp-content\/uploads\/2009\/10\/Fig3-biomechl-language-091005-300x104.png 300w\" sizes=\"(max-width: 328px) 100vw, 328px\" \/><\/p>\n<p>Stiffness is represented by the slope of the straight line on force-displacement diagrams and has units of force per deformation, Newtons per meter (N\/m) or pounds per inch (lb\/in). Stiffer materials, like bone, are more resistant to deformation at a given load than less stiff materials like cartilage [Figure 4].<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-15\" title=\"Fig4 biomechl language 091005\" src=\"http:\/\/www.sgcappsphd.com\/wp-content\/uploads\/2009\/10\/Fig4-biomechl-language-091005.png\" alt=\"Fig4 biomechl language 091005\" width=\"189\" height=\"143\" \/><\/p>\n<h2><strong>Strength, Elasticity, and Viscoelasticity<\/strong><\/h2>\n<p>Although load and strength or stiffness and elasticity are often used interchangeably, they are not the same. Load and stiffness are properties described by force-displacement diagrams while strength and elasticity are properties described by stress versus strain diagrams [Figure 5]. These diagrams are very similar in appearance to load-displacement diagrams, but they represent strength not failure load and elasticity not stiffness.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-16\" title=\"Fig5 biomechl language 091005\" src=\"http:\/\/www.sgcappsphd.com\/wp-content\/uploads\/2009\/10\/Fig5-biomechl-language-091005.png\" alt=\"Fig5 biomechl language 091005\" width=\"220\" height=\"137\" \/><\/p>\n<p>\u201cStress\u201d refers to the forces within an object. The intensity of the internal force over the cut section is stress and is defined as the force per unit area over which the force is acting [\u03c3 = F\/A]. Figure 6 illustrates \u201cnormal stress\u201d, meaning stress that is perpendicular to the plane of the cut; stress is measured as force per unit area and has units of MPa (N\/m2) or psi (lb\/in2). \u201cStrength\u201d is analogous to \u201cfailure load\u201d, it is a measure of the compressive force at the exact instant of failure.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-17\" title=\"Fig6 biomechl language 091005\" src=\"http:\/\/www.sgcappsphd.com\/wp-content\/uploads\/2009\/10\/Fig6-biomechl-language-091005.png\" alt=\"Fig6 biomechl language 091005\" width=\"328\" height=\"175\" srcset=\"https:\/\/sgcappsphd.com\/wp-content\/uploads\/2009\/10\/Fig6-biomechl-language-091005.png 328w, https:\/\/sgcappsphd.com\/wp-content\/uploads\/2009\/10\/Fig6-biomechl-language-091005-300x160.png 300w\" sizes=\"(max-width: 328px) 100vw, 328px\" \/><\/p>\n<p>\u201cStrain\u201d is unit deformation, a measure of the degree or intensity of deformation. Strain is the ratio of change in length (increase or decrease) to original length [\u0454 = \u2206l\/l], and therefore has no units of measure [Figure 7]. When a body is in tension, its length increases and strain is positive. When a body is in compression, its length decreases and strain is negative.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-18\" title=\"Fig7 biomechl language 091005\" src=\"http:\/\/www.sgcappsphd.com\/wp-content\/uploads\/2009\/10\/Fig7-biomechl-language-091005.png\" alt=\"Fig7 biomechl language 091005\" width=\"244\" height=\"130\" \/><\/p>\n<p>\u201cElasticity\u201d is defined by Hooke\u2019s Law, E = \u03c3\/ \u0454, and is represented by the slope of the straight line on stress-strain diagrams. Elasticity has units of MPa or psi. Within the elastic range, the straight line portion of the stress-strain diagram, deformation is reversible by simply removing the load; for example, a rubber band after being stretched will return to it\u2019s original shape. In the non-linear portion of the stress-strain curve, deformation is plastic and non-reversible; potters clay is a good example of \u00a0plastic behavior.<\/p>\n<p>But, few biological tissues obey Hooke\u2019s Law, they actually behave as viscoelastic (a.k.a. viscoplastic) solids. There are two basic properties that describe their behavior: strength and stiffness. Cancellous bone is a viscoplastic biological structure. When cancellous bone is loaded quickly, it behaves as a fairly stiff material, it is resistant to deformation AND it tends to support higher loads. When cancellous bone is loaded slowly, it behaves as a less stiff material. \u201cVisco\u201d because cancellous bone deforms as a function of time. \u201cPlastic\u201d because once it deforms, cancellous bone doesn\u2019t recover much, if any, of its original shape.<\/p>\n<h2><strong>Final Thoughts<\/strong><\/h2>\n<p>This is a very brief \u201ctaste\u201d of biomechanical engineering as it relates to the properties and behavior of orthopaedic tissues. A more detailed discussion would include advanced testing techniques such as impact and fatigue testing, properties like ductility and toughness, and influences from age, gender, and disease.<\/p>\n<p style=\"text-align: center;\"><em>Copyright (c) 2005 \u00a0 \u00a0 \u00a0Susan G. Capps, Ph.D.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Structures and Materials Let\u2019s begin with the difference between \u201cstructures\u201d and \u201cmaterials\u201d. An easy way to remember the distinction is to visualize a building in its early stages of construction. It looks like a huge, complex, erector-set of connected steel beams. The skeletal building is a structure, its properties and behaviors are functions of its [&#8230;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[3,4],"tags":[5],"_links":{"self":[{"href":"https:\/\/sgcappsphd.com\/index.php?rest_route=\/wp\/v2\/posts\/5"}],"collection":[{"href":"https:\/\/sgcappsphd.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sgcappsphd.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sgcappsphd.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/sgcappsphd.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5"}],"version-history":[{"count":18,"href":"https:\/\/sgcappsphd.com\/index.php?rest_route=\/wp\/v2\/posts\/5\/revisions"}],"predecessor-version":[{"id":148,"href":"https:\/\/sgcappsphd.com\/index.php?rest_route=\/wp\/v2\/posts\/5\/revisions\/148"}],"wp:attachment":[{"href":"https:\/\/sgcappsphd.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sgcappsphd.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sgcappsphd.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}